International Scientific Information, Inc. was founded in 2002. The founders, Drs. Mark R. Graczynski and George B. Stefano, emerged from the biomedical community with a vision of creating a scientific and medical publishing enterprise, bringing together medicine and basic research disciplines under one roof. This concept has proven very successful. The business model incorporated the idea that this could be accomplished without generating debt. The company today employs numerous people, taking advantage of a wide array of expertise. It started with one flagship journal, Medical Science Monitor, and now includes four. Our model has proven itself as the business continues to develop and grow. It has been and continues to be an exciting adventure, serving the publishing needs of our colleagues.